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Pk4/2/2024 ![]() However, they usually include jaundice, enlargement of the spleen, and mild or severe hemolysis (red cell breakdown), leading to anemia. The signs and symptoms of the disease may vary greatly from person to person. Without pyruvate kinase, red blood cells break down too easily, resulting in low levels of these cells ( hemolytic anemia). Listen Pyruvate kinase deficiency is a genetic blood disorder characterized by low levels of an enzyme called pyruvate kinase, which is used by red blood cells. Table of Contents expand submenu for Table of Contents.Preguntas Más Frecuentes Sobre los Trastornos Cromosómicos.Consejos Para Obtener Ayuda Financiera Para Una Enfermedad.Consejos Para una Condición no Diagnosticada.Como Encontrar un Especialista en su Enfermedad.Preguntas Más Frecuentes Sobre Enfermedades Raras.Guías de Información expand submenu for Guías de Información.En Español expand submenu for En Español.About GARD expand submenu for About GARD.Teachers and Students expand submenu for Teachers and Students.Researchers expand submenu for Researchers.Caring for Your Patient with a Rare Disease. ![]() Healthcare Professionals expand submenu for Healthcare Professionals.Patients, Families and Friends expand submenu for Patients, Families and Friends.Find Diseases By Category expand submenu for Find Diseases By Category. ![]()
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